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In-Hospital Clinical Outcomes and Procedural Complications of Percutaneous Coronary Intervention in Elderly Patients

BACKGROUND: As population growth leads to an increase in the number of the elderly with coronary artery disease, an evaluation of the clinical outcomes of percutaneous coronary intervention (PCI) in the elderly patients seems to be essential. METHODS: A prospective, observational cohort study was pe...

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Autores principales: Hejazi, Seyed Fakhreddin, Iranirad, Leili, Doostali, Kobra, Khodadadi, Narges, Norouzi, Sameeye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667706/
https://www.ncbi.nlm.nih.gov/pubmed/29118881
http://dx.doi.org/10.14740/cr582e
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author Hejazi, Seyed Fakhreddin
Iranirad, Leili
Doostali, Kobra
Khodadadi, Narges
Norouzi, Sameeye
author_facet Hejazi, Seyed Fakhreddin
Iranirad, Leili
Doostali, Kobra
Khodadadi, Narges
Norouzi, Sameeye
author_sort Hejazi, Seyed Fakhreddin
collection PubMed
description BACKGROUND: As population growth leads to an increase in the number of the elderly with coronary artery disease, an evaluation of the clinical outcomes of percutaneous coronary intervention (PCI) in the elderly patients seems to be essential. METHODS: A prospective, observational cohort study was performed on 468 patients in two groups of elderly and non-elderly patients (mean age: 60.01 ± 10.84 years; ≥ 70 years, 20.1%; men, 62%) who underwent PCI, to evaluate the procedural success and in-hospital major and minor adverse cardiovascular events in the elderly patients. RESULTS: The procedural success rate was significantly lower (95.7% vs. 99.5%, P = 0.017) and the rates of in-hospital complications were significantly higher (10.6% vs. 0.8%, P < 0.0001) in elderly (+70) than in non-elderly patients. On the basis of a multivariate analysis, being elderly was not an independent predictor of procedural failure, but increased the chance of in-hospital complications to 8% higher (odds ratio: 0.08; 95% confidence interval: 0.01 - 0.39; P = 0.002). CONCLUSION: Regardless of the difference in the procedural success and in-hospital complication rates between our two study groups, aging is not an important predictor of them. Furthermore, PCI should not be refused in elderly patients if indicated.
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spelling pubmed-56677062017-11-08 In-Hospital Clinical Outcomes and Procedural Complications of Percutaneous Coronary Intervention in Elderly Patients Hejazi, Seyed Fakhreddin Iranirad, Leili Doostali, Kobra Khodadadi, Narges Norouzi, Sameeye Cardiol Res Original Article BACKGROUND: As population growth leads to an increase in the number of the elderly with coronary artery disease, an evaluation of the clinical outcomes of percutaneous coronary intervention (PCI) in the elderly patients seems to be essential. METHODS: A prospective, observational cohort study was performed on 468 patients in two groups of elderly and non-elderly patients (mean age: 60.01 ± 10.84 years; ≥ 70 years, 20.1%; men, 62%) who underwent PCI, to evaluate the procedural success and in-hospital major and minor adverse cardiovascular events in the elderly patients. RESULTS: The procedural success rate was significantly lower (95.7% vs. 99.5%, P = 0.017) and the rates of in-hospital complications were significantly higher (10.6% vs. 0.8%, P < 0.0001) in elderly (+70) than in non-elderly patients. On the basis of a multivariate analysis, being elderly was not an independent predictor of procedural failure, but increased the chance of in-hospital complications to 8% higher (odds ratio: 0.08; 95% confidence interval: 0.01 - 0.39; P = 0.002). CONCLUSION: Regardless of the difference in the procedural success and in-hospital complication rates between our two study groups, aging is not an important predictor of them. Furthermore, PCI should not be refused in elderly patients if indicated. Elmer Press 2017-10 2017-10-27 /pmc/articles/PMC5667706/ /pubmed/29118881 http://dx.doi.org/10.14740/cr582e Text en Copyright 2017, Hejazi et al. http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Non-Commercial 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Hejazi, Seyed Fakhreddin
Iranirad, Leili
Doostali, Kobra
Khodadadi, Narges
Norouzi, Sameeye
In-Hospital Clinical Outcomes and Procedural Complications of Percutaneous Coronary Intervention in Elderly Patients
title In-Hospital Clinical Outcomes and Procedural Complications of Percutaneous Coronary Intervention in Elderly Patients
title_full In-Hospital Clinical Outcomes and Procedural Complications of Percutaneous Coronary Intervention in Elderly Patients
title_fullStr In-Hospital Clinical Outcomes and Procedural Complications of Percutaneous Coronary Intervention in Elderly Patients
title_full_unstemmed In-Hospital Clinical Outcomes and Procedural Complications of Percutaneous Coronary Intervention in Elderly Patients
title_short In-Hospital Clinical Outcomes and Procedural Complications of Percutaneous Coronary Intervention in Elderly Patients
title_sort in-hospital clinical outcomes and procedural complications of percutaneous coronary intervention in elderly patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667706/
https://www.ncbi.nlm.nih.gov/pubmed/29118881
http://dx.doi.org/10.14740/cr582e
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