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Nanobodies targeting norovirus capsid reveal functional epitopes and potential mechanisms of neutralization

Norovirus is the leading cause of gastroenteritis worldwide. Despite recent developments in norovirus propagation in cell culture, these viruses are still challenging to grow routinely. Moreover, little is known on how norovirus infects the host cells, except that histo-blood group antigens (HBGAs)...

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Detalles Bibliográficos
Autores principales: Koromyslova, Anna D., Hansman, Grant S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667739/
https://www.ncbi.nlm.nih.gov/pubmed/29095961
http://dx.doi.org/10.1371/journal.ppat.1006636