MIF inhibition interferes with the inflammatory and T cell-stimulatory capacity of NOD macrophages and delays autoimmune diabetes onset

Macrophages contribute in the initiation and progression of insulitis during type 1 diabetes (T1D). However, the mechanisms governing their recruitment into the islets as well as the manner of retention and activation are incompletely understood. Here, we investigated a role for macrophage migration...

Descripción completa

Detalles Bibliográficos
Autores principales: Korf, Hannelie, Breser, Laura, Van Hoeck, Jelter, Godoy, Janet, Cook, Dana P., Stijlemans, Benoit, De Smidt, Elien, Moyson, Carolien, Monteiro Carvalho Mori Cunha, João Paulo, Rivero, Virginia, Gysemans, Conny, Mathieu, Chantal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667746/
https://www.ncbi.nlm.nih.gov/pubmed/29095944
http://dx.doi.org/10.1371/journal.pone.0187455

Ejemplares similares

Ejemplares similares