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Activation of Notch1 signaling alleviates dysfunction of bone marrow-derived mesenchymal stem cells induced by cigarette smoke extract

Bone marrow-derived mesenchymal stem cells (BM-MSCs) are considered attractive therapeutic agents for the treatment of COPD. However, little is known about the impact of Notch on the proliferation, migration, and survival of MSCs in a cigarette smoke (CS) microenvironment. Here, we used CS extract t...

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Detalles Bibliográficos
Autores principales: Cheng, Yi, Gu, Wen, Zhang, Guorui, Li, Xiaoming, Guo, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667796/
https://www.ncbi.nlm.nih.gov/pubmed/29138545
http://dx.doi.org/10.2147/COPD.S146201

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