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Activation of Notch1 signaling alleviates dysfunction of bone marrow-derived mesenchymal stem cells induced by cigarette smoke extract
Bone marrow-derived mesenchymal stem cells (BM-MSCs) are considered attractive therapeutic agents for the treatment of COPD. However, little is known about the impact of Notch on the proliferation, migration, and survival of MSCs in a cigarette smoke (CS) microenvironment. Here, we used CS extract t...
Autores principales: | Cheng, Yi, Gu, Wen, Zhang, Guorui, Li, Xiaoming, Guo, Xuejun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667796/ https://www.ncbi.nlm.nih.gov/pubmed/29138545 http://dx.doi.org/10.2147/COPD.S146201 |
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