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Recovery from impaired muscle growth arises from prolonged postnatal accretion of myonuclei in Atrx mutant mice
Reduced muscle mass due to pathological development can occur through several mechanisms, including the loss or reduced proliferation of muscle stem cells. Muscle-specific ablation of the α-thalassemia mental retardation syndrome mutant protein, Atrx, in transgenic mice results in animals with a sev...
Autores principales: | Huh, Michael S., Young, Kevin G., Yan, Keqin, Price-O’Dea, Tina, Picketts, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667798/ https://www.ncbi.nlm.nih.gov/pubmed/29095838 http://dx.doi.org/10.1371/journal.pone.0186989 |
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