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Effects of AMPD1 common mutation on the metabolic-chronotropic relationship: Insights from patients with myoadenylate deaminase deficiency

PURPOSE: Current evidence indicates that the common AMPD1 gene variant is associated with improved survival in patients with advanced heart failure. Whilst adenosine has been recognized to mediate the cardioprotective effect of C34T AMPD1, the precise pathophysiologic mechanism involved remains unde...

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Detalles Bibliográficos
Autores principales: Rannou, Fabrice, Scotet, Virginie, Marcorelles, Pascale, Monnoyer, Roxane, Le Maréchal, Cédric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667816/
https://www.ncbi.nlm.nih.gov/pubmed/29095874
http://dx.doi.org/10.1371/journal.pone.0187266

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