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TRIM5α SPRY/coiled-coil interactions optimize avid retroviral capsid recognition
Restriction factors are important components of intrinsic cellular defense mechanisms against viral pathogens. TRIM5α is a restriction factor that intercepts the incoming capsid cores of retroviruses such as HIV and provides an effective species-specific barrier to retroviral infection. The TRIM5α S...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667893/ https://www.ncbi.nlm.nih.gov/pubmed/29040325 http://dx.doi.org/10.1371/journal.ppat.1006686 |