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Transcriptional signature of lymphoblastoid cell lines of BRCA1, BRCA2 and non-BRCA1/2 high risk breast cancer families

Approximately 25% of hereditary breast cancer cases are associated with a strong familial history which can be explained by mutations in BRCA1 or BRCA2 and other lower penetrance genes. The remaining high-risk families could be classified as BRCAX (non-BRCA1/2) families. Gene expression involving al...

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Detalles Bibliográficos
Autores principales: Pouliot, Marie-Christine, Kothari, Charu, Joly-Beauparlant, Charles, Labrie, Yvan, Ouellette, Geneviève, Simard, Jacques, Droit, Arnaud, Durocher, Francine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667991/
https://www.ncbi.nlm.nih.gov/pubmed/29108258
http://dx.doi.org/10.18632/oncotarget.20219