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CT-guided microwave ablation through the lungs for treating liver tumors near the diaphragm
PURPOSE: To explore the short-term efficacy and safety of CT-guided microwave ablation (MWA) for treating liver tumors near the diaphragm. RESULTS: The complete response (CR) rate for CT-guided MWA through the lung was 94.7% (124/131). The incomplete response (ICR) rate was 5.3% (7/131), of which 6...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668038/ https://www.ncbi.nlm.nih.gov/pubmed/29108305 http://dx.doi.org/10.18632/oncotarget.17422 |
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author | Qi, Han Zhang, Hao Wan, Chao Xie, Lin Song, Ze Fan, Weijun |
author_facet | Qi, Han Zhang, Hao Wan, Chao Xie, Lin Song, Ze Fan, Weijun |
author_sort | Qi, Han |
collection | PubMed |
description | PURPOSE: To explore the short-term efficacy and safety of CT-guided microwave ablation (MWA) for treating liver tumors near the diaphragm. RESULTS: The complete response (CR) rate for CT-guided MWA through the lung was 94.7% (124/131). The incomplete response (ICR) rate was 5.3% (7/131), of which 6 patients with ICRs achieved CRs after MWA. The CR rate for Group I was higher than Group II (99.0% vs. 80.0%, P=0.001). The mean follow-up time was 11.2 ±7.50 months. The total local recurrence (LR) rate was 15.3% (20/131). The complication rate was 26.5%, and no severe complications were recorded. All complications were controllable and treatable. The incidence of diaphragmatic thickening during the MWA was 18.8% (P>0.05); the incidence of exudative changes inside the lungs was 6.8% (P>0.05). CONCLUSIONS: CT-guided MWA can detect changes in liver tissue, in the diaphragm and nearby lung tissues during the ablation process. It’s safe and effective to treat tumors close to the diaphragm by CT-guided MWA through the lung. METHODS: CT-guided MWA was used on 131 tumors that were close to the diaphragm (distance between tumor and diaphragm ≤ 5 mm) in 117 patients with liver cancer. The tumors were divided into a < 3.0 cm group (Group I, n= 101) and a ≥ 3.0 cm group (Group II, n= 30) based on tumor diameters. The complications within 2 weeks following treatment were counted, and the safety and short-term efficacy of MWA were analyzed. |
format | Online Article Text |
id | pubmed-5668038 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Impact Journals LLC |
record_format | MEDLINE/PubMed |
spelling | pubmed-56680382017-11-04 CT-guided microwave ablation through the lungs for treating liver tumors near the diaphragm Qi, Han Zhang, Hao Wan, Chao Xie, Lin Song, Ze Fan, Weijun Oncotarget Clinical Research Paper PURPOSE: To explore the short-term efficacy and safety of CT-guided microwave ablation (MWA) for treating liver tumors near the diaphragm. RESULTS: The complete response (CR) rate for CT-guided MWA through the lung was 94.7% (124/131). The incomplete response (ICR) rate was 5.3% (7/131), of which 6 patients with ICRs achieved CRs after MWA. The CR rate for Group I was higher than Group II (99.0% vs. 80.0%, P=0.001). The mean follow-up time was 11.2 ±7.50 months. The total local recurrence (LR) rate was 15.3% (20/131). The complication rate was 26.5%, and no severe complications were recorded. All complications were controllable and treatable. The incidence of diaphragmatic thickening during the MWA was 18.8% (P>0.05); the incidence of exudative changes inside the lungs was 6.8% (P>0.05). CONCLUSIONS: CT-guided MWA can detect changes in liver tissue, in the diaphragm and nearby lung tissues during the ablation process. It’s safe and effective to treat tumors close to the diaphragm by CT-guided MWA through the lung. METHODS: CT-guided MWA was used on 131 tumors that were close to the diaphragm (distance between tumor and diaphragm ≤ 5 mm) in 117 patients with liver cancer. The tumors were divided into a < 3.0 cm group (Group I, n= 101) and a ≥ 3.0 cm group (Group II, n= 30) based on tumor diameters. The complications within 2 weeks following treatment were counted, and the safety and short-term efficacy of MWA were analyzed. Impact Journals LLC 2017-04-26 /pmc/articles/PMC5668038/ /pubmed/29108305 http://dx.doi.org/10.18632/oncotarget.17422 Text en Copyright: © 2017 Qi et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Clinical Research Paper Qi, Han Zhang, Hao Wan, Chao Xie, Lin Song, Ze Fan, Weijun CT-guided microwave ablation through the lungs for treating liver tumors near the diaphragm |
title | CT-guided microwave ablation through the lungs for treating liver tumors near the diaphragm |
title_full | CT-guided microwave ablation through the lungs for treating liver tumors near the diaphragm |
title_fullStr | CT-guided microwave ablation through the lungs for treating liver tumors near the diaphragm |
title_full_unstemmed | CT-guided microwave ablation through the lungs for treating liver tumors near the diaphragm |
title_short | CT-guided microwave ablation through the lungs for treating liver tumors near the diaphragm |
title_sort | ct-guided microwave ablation through the lungs for treating liver tumors near the diaphragm |
topic | Clinical Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668038/ https://www.ncbi.nlm.nih.gov/pubmed/29108305 http://dx.doi.org/10.18632/oncotarget.17422 |
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