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Utf1 contributes to intergenerational epigenetic inheritance of pluripotency

Undifferentiated embryonic cell transcription factor 1 (Utf1) is expressed in pluripotent embryonic stem cells (ESCs) and primordial germ cells (PGCs). Utf1 expression is directly controlled by pluripotency factors Oct4 and Sox2, which form a ternary complex with the Utf1 enhancer. The Utf1 protein...

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Detalles Bibliográficos
Autores principales:	Bao, Qiuye, Morshedi, Amir, Wang, Fulu, Bhargy, Sharma, Pervushin, Konstantin, Yu, Wei-Ping, Dröge, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668265/ https://www.ncbi.nlm.nih.gov/pubmed/29097685 http://dx.doi.org/10.1038/s41598-017-14426-5

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