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HIF-1α- Targeting Acriflavine Provides Long Term Survival and Radiological Tumor Response in Brain Cancer Therapy

Tumor progression, limited efficacy of current standard treatments, and the rise in patient mortality are associated with gene expression caused by the synergistic action of intratumoral hypoxia and HIF-1α activation. For this reason, recent investigations have focused on HIF-targeting therapeutic a...

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Detalles Bibliográficos
Autores principales:	Mangraviti, Antonella, Raghavan, Tula, Volpin, Francesco, Skuli, Nicolas, Gullotti, David, Zhou, Jinyuan, Asnaghi, Laura, Sankey, Eric, Liu, Ann, Wang, Yuan, Lee, Dong-Hoon, Gorelick, Noah, Serra, Riccardo, Peters, Michael, Schriefer, Destiny, Delaspre, Fabien, Rodriguez, Fausto J., Eberhart, Charles G., Brem, Henry, Olivi, Alessandro, Tyler, Betty
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668269/ https://www.ncbi.nlm.nih.gov/pubmed/29097800 http://dx.doi.org/10.1038/s41598-017-14990-w

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