Functional coupling of human pancreatic islets and liver spheroids on-a-chip: Towards a novel human ex vivo type 2 diabetes model

Human in vitro physiological models studying disease and drug treatment effects are urgently needed as more relevant tools to identify new drug targets and therapies. We have developed a human microfluidic two-organ-chip model to study pancreatic islet–liver cross-talk based on insulin and glucose r...

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Detalles Bibliográficos
Autores principales: Bauer, Sophie, Wennberg Huldt, Charlotte, Kanebratt, Kajsa P., Durieux, Isabell, Gunne, Daniela, Andersson, Shalini, Ewart, Lorna, Haynes, William G., Maschmeyer, Ilka, Winter, Annika, Ämmälä, Carina, Marx, Uwe, Andersson, Tommy B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668271/
https://www.ncbi.nlm.nih.gov/pubmed/29097671
http://dx.doi.org/10.1038/s41598-017-14815-w

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