Genome-scale single-cell mechanical phenotyping reveals disease-related genes involved in mitotic rounding

To divide, most animal cells drastically change shape and round up against extracellular confinement. Mitotic cells facilitate this process by generating intracellular pressure, which the contractile actomyosin cortex directs into shape. Here, we introduce a genome-scale microcantilever- and RNAi-ba...

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Detalles Bibliográficos
Autores principales: Toyoda, Yusuke, Cattin, Cedric J., Stewart, Martin P., Poser, Ina, Theis, Mirko, Kurzchalia, Teymuras V., Buchholz, Frank, Hyman, Anthony A., Müller, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668354/
https://www.ncbi.nlm.nih.gov/pubmed/29097687
http://dx.doi.org/10.1038/s41467-017-01147-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668354/
https://www.ncbi.nlm.nih.gov/pubmed/29097687
http://dx.doi.org/10.1038/s41467-017-01147-6

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