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Structural Insight into Inhibition of CsrA-RNA Interaction Revealed by Docking, Molecular Dynamics and Free Energy Calculations

The carbon storage regulator A (CsrA) and its homologs play an important role in coordinating the expression of bacterial virulence factors required for successful host infection. In addition, bacterial pathogens with deficiency of CsrA are typically attenuated for virulence. In 2016, the first seri...

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Detalles Bibliográficos
Autores principales:	Ren, Xiaodong, Zeng, Rui, Tortorella, Micky, Wang, Jinming, Wang, Changwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668361/ https://www.ncbi.nlm.nih.gov/pubmed/29097778 http://dx.doi.org/10.1038/s41598-017-14916-6

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