Cargando…

Discovery of targetable genetic alterations in advanced non-small cell lung cancer using a next-generation sequencing-based circulating tumor DNA assay

Next-generation sequencing (NGS)-based circulating tumor DNA (ctDNA) assays have provided a new method of identifying tumor-driving genes in patients with advanced non-small cell lung carcinoma (NSCLC), especially in those whose cancer tissues are unavailable or in those that have acquired treatment...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hou, Helei, Yang, Xiaonan, Zhang, Jinping, Zhang, Zhe, Xu, Xiaomei, Zhang, Xiaoping, Zhang, Chuantao, Liu, Dong, Yan, Weihua, Zhou, Na, Zhu, Hongmei, Qian, Zhaoyang, Li, Zhuokun, Zhang, Xiaochun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668369/ https://www.ncbi.nlm.nih.gov/pubmed/29097733 http://dx.doi.org/10.1038/s41598-017-14962-0

Ejemplares similares

Publisher Correction: Discovery of targetable genetic alterations in advanced non-small cell lung cancer using a next-generation sequencing-based circulating tumor DNA assay
por: Hou, Helei, et al.
Publicado: (2018)

Targeted next generation sequencing in Chinese colorectal cancer patients guided anti-EGFR treatment and facilitated precision cancer medicine
por: Hou, Helei, et al.
Publicado: (2017)

KIT/PDGFRA/KDR amplification defines a novel molecular subtype of adenoid cystic carcinoma patients who may benefit from treatment with tyrosine kinase inhibitors
por: Hou, Helei, et al.
Publicado: (2020)

The efficacy and safety of apatinib for refractory malignancies: a review and meta-analysis
por: Sun, Dantong, et al.
Publicado: (2018)

Chemotherapy Alters the Phylogenetic Molecular Ecological Networks of Intestinal Microbial Communities
por: Cong, Jing, et al.
Publicado: (2019)

ALK rearrangements as mechanisms of acquired resistance to osimertinib in EGFR mutant non‐small cell lung cancer
por: Hou, Helei, et al.
Publicado: (2021)

Neoadjuvant PD-1 blockade plus chemotherapy versus chemotherapy alone in locally advanced stage II-III gastric cancer: A single-centre retrospective study
por: Zhang, Xuchen, et al.
Publicado: (2023)

Use tumor suppressor genes as biomarkers for diagnosis of non-small cell lung cancer
por: Zhang, Chuantao, et al.
Publicado: (2021)

Response to apatinib in chemotherapy-failed advanced spindle cell breast carcinoma
por: Zhou, Na, et al.
Publicado: (2016)

Progress in the treatment of solid tumors with apatinib: a systematic review
por: Zhao, Deze, et al.
Publicado: (2018)

The role of MDM2 amplification and overexpression in therapeutic resistance of malignant tumors
por: Hou, Helei, et al.
Publicado: (2019)

Anlotinib Combined with Toripalimab as Second-Line Therapy for Advanced, Relapsed Gastric or Gastroesophageal Junction Carcinoma
por: Jiang, Man, et al.
Publicado: (2022)

Concurrent TP53 mutations predict poor outcomes of EGFR-TKI treatments in Chinese patients with advanced NSCLC
por: Hou, Helei, et al.
Publicado: (2019)

The role of RICTOR amplification in targeted therapy and drug resistance
por: Zhao, Deze, et al.
Publicado: (2020)

Prognostic value of TP53 concurrent mutations for EGFR- TKIs and ALK-TKIs based targeted therapy in advanced non-small cell lung cancer: a meta-analysis
por: Qin, Kang, et al.
Publicado: (2020)

Comprehensive analysis of genomic alterations detected by next-generation sequencing-based tissue and circulating tumor DNA assays in Chinese patients with non-small cell lung cancer
por: Yang, Hua, et al.
Publicado: (2019)

Apatinib suppresses cell growth and metastasis and promotes antitumor activity of temozolomide in glioma
por: Wang, Chao, et al.
Publicado: (2018)

The safety and serious adverse events of approved ALK inhibitors in malignancies: a meta-analysis
por: Hou, Helei, et al.
Publicado: (2019)

Theoretical studies on glycolysis of poly(ethylene terephthalate) in ionic liquids
por: Ju, Zhaoyang, et al.
Publicado: (2018)

A MicroRNA Next-Generation-Sequencing Discovery Assay (miND) for Genome-Scale Analysis and Absolute Quantitation of Circulating MicroRNA Biomarkers
por: Khamina, Kseniya, et al.
Publicado: (2022)

Discovery of Targetable Genetic Alterations in NSCLC Patients with Different Metastatic Patterns Using a MassARRAY-Based Circulating Tumor DNA Assay
por: Belloum, Yassine, et al.
Publicado: (2020)

Case Report: Primary and Acquired Resistance Mechanisms of Nimotuzumab in Advanced Esophageal Squamous Cell Carcinoma Revealed by Targeted Sequencing
por: Sun, Dantong, et al.
Publicado: (2020)

The utility of folate receptor-positive circulating tumor cell in cancer diagnosis in the elderly population
por: Li, Na, et al.
Publicado: (2019)

Apatinib in Combination with S‐1 as First‐Line Treatment in Patients with Advanced Metastatic Gastric Cancer: Results from an Open, Exploratory, Single‐Arm, Phase II Trial
por: Zhou, Na, et al.
Publicado: (2020)

The BioAssay network and its implications to future therapeutic discovery
por: Zhang, Jintao, et al.
Publicado: (2011)

Risk Stratification Study of Indeterminate Thyroid Nodules with a next-generation Sequencing Assay with Residual ThinPrep® Material
por: Zhao, Huan, et al.
Publicado: (2020)

Circulating Tumor DNA Characteristics Based on Next Generation Sequencing and Its Correlation With Clinical Parameters in Patients With Lymphoma
por: Wu, Xiao-Bo, et al.
Publicado: (2022)

Assessing Clinical Outcomes in Colorectal Cancer with Assays for Invasive Circulating Tumor Cells
por: Zhang, Yue, et al.
Publicado: (2018)

Evaluation of Circulating Endothelial Progenitor Cells in Abdominal Aortic Aneurysms after Endovascular Aneurysm Repair
por: Wu, Weihua, et al.
Publicado: (2021)

Discovery of Novel Circulating Immune Complexes in Lupus Nephritis Using Immunoproteomics
por: Tang, Chenling, et al.
Publicado: (2022)

The Discovery of the Circulation of the Blood
Publicado: (1923)

Metabolic alteration of circulating steroid hormones in women with gestational diabetes mellitus and the related risk factors
por: Yang, Na, et al.
Publicado: (2023)

Antiangiogenesis Combined with Immunotherapy to Treat Advanced Small-Cell Carcinoma of the Esophagus Resistant to Chemotherapy: According to the Guidance of Next-Generation Sequencing
por: Jiang, Man, et al.
Publicado: (2021)

Field comparison of circulating antibody assays versus circulating antigen assays for the detection of schistosomiasis japonica in endemic areas of China
por: Cai, Yu-Chun, et al.
Publicado: (2014)

A Cluster-Based Approach for the Discovery of Copy Number Variations From Next-Generation Sequencing Data
por: Liu, Guojun, et al.
Publicado: (2021)

Next‐Generation Sequencing of Circulating Tumor DNA Reveals Frequent Alterations in Advanced Hepatocellular Carcinoma
por: Ikeda, Sadakatsu, et al.
Publicado: (2018)

Genome‐wide genetic variation discovery in Chinese Taihu pig breeds using next generation sequencing
por: Wang, Z., et al.
Publicado: (2016)

Analytical and clinical validation of an amplicon-based next generation sequencing assay for ultrasensitive detection of circulating tumor DNA
por: Poh, Jonathan, et al.
Publicado: (2022)

Targeted next-generation sequencing identified a known EMD mutation in a Chinese patient with Emery-Dreifuss muscular dystrophy
por: Dai, Xiafei, et al.
Publicado: (2019)

SNP Discovery in the Transcriptome of White Pacific Shrimp Litopenaeus vannamei by Next Generation Sequencing
por: Yu, Yang, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_7rtvkqlspfsjhsnrnhclch4hkp