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Quantitative structural mechanobiology of platelet-driven blood clot contraction

Blood clot contraction plays an important role in prevention of bleeding and in thrombotic disorders. Here, we unveil and quantify the structural mechanisms of clot contraction at the level of single platelets. A key elementary step of contraction is sequential extension–retraction of platelet filop...

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Detalles Bibliográficos
Autores principales: Kim, Oleg V., Litvinov, Rustem I., Alber, Mark S., Weisel, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668372/
https://www.ncbi.nlm.nih.gov/pubmed/29097692
http://dx.doi.org/10.1038/s41467-017-00885-x