Phenotypic variability in LQT3 human induced pluripotent stem cell-derived cardiomyocytes and their response to antiarrhythmic pharmacologic therapy: An in silico approach

BACKGROUND: Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are in vitro models with the clear advantages of their human origin and suitability for human disease investigations. However, limitations include their incomplete characterization and variability reported in differen...

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Detalles Bibliográficos
Autores principales: Paci, Michelangelo, Passini, Elisa, Severi, Stefano, Hyttinen, Jari, Rodriguez, Blanca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668441/
https://www.ncbi.nlm.nih.gov/pubmed/28756098
http://dx.doi.org/10.1016/j.hrthm.2017.07.026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668441/
https://www.ncbi.nlm.nih.gov/pubmed/28756098
http://dx.doi.org/10.1016/j.hrthm.2017.07.026

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