Research progress on the relationship between zinc deficiency, related microRNAs, and esophageal carcinoma

Esophageal cancer (EC) is a common malignant tumor of the gastrointestinal tract with a high incidence in China. Zinc (Zn) deficiency is a key risk factor for the occurrence and development of EC and affects progression by regulating microRNA (miRNA, miR) expression. In addition, the dysregulation o...

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Detalles Bibliográficos
Autores principales: Liu, Cong‐Min, Liang, Di, Jin, Jing, Li, Dao‐Juan, Zhang, Ya‐Chen, Gao, Zhao‐Yu, He, Yu‐Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2017
Materias:
Mini Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668500/
https://www.ncbi.nlm.nih.gov/pubmed/28892299
http://dx.doi.org/10.1111/1759-7714.12493
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author Liu, Cong‐Min
Liang, Di
Jin, Jing
Li, Dao‐Juan
Zhang, Ya‐Chen
Gao, Zhao‐Yu
He, Yu‐Tong
author_facet Liu, Cong‐Min
Liang, Di
Jin, Jing
Li, Dao‐Juan
Zhang, Ya‐Chen
Gao, Zhao‐Yu
He, Yu‐Tong
author_sort Liu, Cong‐Min
collection PubMed
description Esophageal cancer (EC) is a common malignant tumor of the gastrointestinal tract with a high incidence in China. Zinc (Zn) deficiency is a key risk factor for the occurrence and development of EC and affects progression by regulating microRNA (miRNA, miR) expression. In addition, the dysregulation of miRNAs is accompanied by the dysregulation of their target genes in EC. In this paper, we review the potential molecular mechanisms between Zn deficiency and EC with the aim of providing new strategies and methods for early diagnosis, targeted therapy, and prognostic evaluation.
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spelling pubmed-56685002017-11-09 Research progress on the relationship between zinc deficiency, related microRNAs, and esophageal carcinoma Liu, Cong‐Min Liang, Di Jin, Jing Li, Dao‐Juan Zhang, Ya‐Chen Gao, Zhao‐Yu He, Yu‐Tong Thorac Cancer Mini Review Esophageal cancer (EC) is a common malignant tumor of the gastrointestinal tract with a high incidence in China. Zinc (Zn) deficiency is a key risk factor for the occurrence and development of EC and affects progression by regulating microRNA (miRNA, miR) expression. In addition, the dysregulation of miRNAs is accompanied by the dysregulation of their target genes in EC. In this paper, we review the potential molecular mechanisms between Zn deficiency and EC with the aim of providing new strategies and methods for early diagnosis, targeted therapy, and prognostic evaluation. John Wiley & Sons Australia, Ltd 2017-09-11 2017-11 /pmc/articles/PMC5668500/ /pubmed/28892299 http://dx.doi.org/10.1111/1759-7714.12493 Text en © 2017 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Mini Review
Liu, Cong‐Min
Liang, Di
Jin, Jing
Li, Dao‐Juan
Zhang, Ya‐Chen
Gao, Zhao‐Yu
He, Yu‐Tong
Research progress on the relationship between zinc deficiency, related microRNAs, and esophageal carcinoma
title Research progress on the relationship between zinc deficiency, related microRNAs, and esophageal carcinoma
title_full Research progress on the relationship between zinc deficiency, related microRNAs, and esophageal carcinoma
title_fullStr Research progress on the relationship between zinc deficiency, related microRNAs, and esophageal carcinoma
title_full_unstemmed Research progress on the relationship between zinc deficiency, related microRNAs, and esophageal carcinoma
title_short Research progress on the relationship between zinc deficiency, related microRNAs, and esophageal carcinoma
title_sort research progress on the relationship between zinc deficiency, related micrornas, and esophageal carcinoma
topic Mini Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668500/
https://www.ncbi.nlm.nih.gov/pubmed/28892299
http://dx.doi.org/10.1111/1759-7714.12493
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