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Concurrent epidermal growth factor receptor T790M secondary mutation and epithelial‐mesenchymal transition in a lung adenocarcinoma patient with EGFR‐TKI drug resistance

Almost all epidermal growth factor receptor (EGFR)‐mutant lung cancers develop resistance to EGFR‐tyrosine kinase inhibitors. Several mechanisms for this acquired resistance have been identified, including development of an EGFR T790M mutation, MET amplification, hepatocyte growth factor overexpress...

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Detalles Bibliográficos
Autores principales:	Xu, Song, Liu, Xia, Liu, Renwang, Shi, Tao, Li, Xiongfei, Zhong, Diansheng, Wang, Yan, Chen, Gang, Chen, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons Australia, Ltd 2017
Materias:	Case Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668506/ https://www.ncbi.nlm.nih.gov/pubmed/28786540 http://dx.doi.org/10.1111/1759-7714.12484

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