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Patient harboring a novel PIK3CA point mutation after acquired resistance to crizotinib in an adenocarcinoma with ROS1 rearrangement: A case report and literature review
ROS1 rearrangement occurs in 1–2% of non‐small cell lung cancer (NSCLC) cases. These patients would benefit from treatment with the anaplastic lymphoma kinase inhibitor, crizotinib; however, resistance to crizotinib inevitably develops in such patients despite an initial response. The mechanism of a...
Autores principales: | Xu, Chun‐wei, Wang, Wen‐xian, Huang, Rong‐fang, He, Cheng, Liao, Xing‐hui, Zhu, You‐cai, Du, Kai‐qi, Zhuang, Wu, Chen, Yan‐ping, Chen, Gang, Fang, Mei‐yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons Australia, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668514/ https://www.ncbi.nlm.nih.gov/pubmed/28845578 http://dx.doi.org/10.1111/1759-7714.12496 |
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