Cargando…

Novel acidic phospholipase A(2) from Porthidium hyoprora causes inflammation with mast cell rich infiltrate

Phospholipases A(2) (PLA(2)) are a group of enzymes that hydrolyze phospholipids at the sn-2 position, being present in all nature. In venomous animals, these proteins assume a special role, being able to exert diverse pharmacological effects. In this work, authors identified a new isoform of PLA(2)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marques, Petrus Pires, Esteves, Alessandra, Lancellotti, Marcelo, Ponce-Soto, Luis Alberto, Marangoni, Sergio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668520/ https://www.ncbi.nlm.nih.gov/pubmed/29124136 http://dx.doi.org/10.1016/j.bbrep.2015.03.001

Ejemplares similares

Chemical Modifications of PhTX-I Myotoxin from Porthidium hyoprora Snake Venom: Effects on Structural, Enzymatic, and Pharmacological Properties
por: Huancahuire-Vega, Salomón, et al.
Publicado: (2013)

PhTX-II a Basic Myotoxic Phospholipase A(2) from Porthidium hyoprora Snake Venom, Pharmacological Characterization and Amino Acid Sequence by Mass Spectrometry
por: Huancahuire-Vega, Salomón, et al.
Publicado: (2014)

Differential Antivenom and Small-Molecule Inhibition of Novel Coagulotoxic Variations in Atropoides, Cerrophidion, Metlapilcoatlus, and Porthidium American Viperid Snake Venoms
por: Jones, Lee, et al.
Publicado: (2022)

Comparative Analysis of Alpha-1 Orthosteric-Site Binding by a Clade of Central American Pit Vipers (Genera Atropoides, Cerrophidion, Metlapilcoatlus, and Porthidium)
por: Jones, Lee, et al.
Publicado: (2023)

Possible Involvement of Intracellular Calcium-Independent Phospholipase A(2) in the Release of Secretory Phospholipases from Mast Cells—Increased Expression in Ileal Mast Cells of Crohn’s Disease
por: Christerson, Ulrika, et al.
Publicado: (2019)

Mast Cell-Specific Deletion of Group III Secreted Phospholipase A(2) Impairs Mast Cell Maturation and Functions
por: Taketomi, Yoshitaka, et al.
Publicado: (2021)

Infiltration of mast cells in pachydermia of pachydermoperiostosis
por: Tanese, Keiji, et al.
Publicado: (2017)

Induction of Mast-Cell Accumulation by Promutoxin, an Arg-49 Phospholipase A(2)
por: Wei, Ji-Fu, et al.
Publicado: (2013)

The Influence of Polyunsaturated Fatty Acids on the Phospholipase D Isoforms Trafficking and Activity in Mast Cells
por: Basiouni, Shereen, et al.
Publicado: (2013)

Regulatory Roles of Phospholipase A(2) Enzymes and Bioactive Lipids in Mast Cell Biology
por: Taketomi, Yoshitaka, et al.
Publicado: (2022)

Phospholipase D2 Modulates the Secretory Pathway in RBL-2H3 Mast Cells
por: Marchini-Alves, Claudia Maria Meirelles, et al.
Publicado: (2015)

Levels of circulating mast cell progenitors and tumour-infiltrating mast cells in patients with colorectal cancer
por: Zhao, Pingwei, et al.
Publicado: (2022)

Association of mast cell infiltration with gastric cancer progression
por: Zhong, Bei, et al.
Publicado: (2018)

Unmasking Snake Venom of Bothrops leucurus: Purification and Pharmacological and Structural Characterization of New PLA(2) Bleu TX-III
por: Marangoni, Fábio André, et al.
Publicado: (2013)

Induction of mast cell accumulation, histamine release and skin edema by N49 phospholipase A(2)
por: Wei, Ji-Fu, et al.
Publicado: (2009)

Augmented mast cell infiltration and microvessel density in prostate cancer
por: Stawerski, Paweł, et al.
Publicado: (2013)

Presumed mast cell choroidal infiltrate in aggressive systemic mastocytosis
por: Tran, Tu M., et al.
Publicado: (2020)

Mast cells in meningiomas and brain inflammation
por: Polyzoidis, Stavros, et al.
Publicado: (2015)

Toxoplasma gondii inhibits mast cell degranulation by suppressing phospholipase Cγ-mediated Ca(2+) mobilization
por: Smith, Norah L., et al.
Publicado: (2013)

New Concepts in Phospholipase D Signaling in Inflammation and Cancer
por: Gomez-Cambronero, Julian
Publicado: (2010)

Triple-Negative Breast Cancer with High Levels of Annexin A1 Expression Is Associated with Mast Cell Infiltration, Inflammation, and Angiogenesis
por: Okano, Maiko, et al.
Publicado: (2019)

Psoriatic T cells recognize neolipid antigens generated by mast cell phospholipase delivered by exosomes and presented by CD1a
por: Cheung, Ka Lun, et al.
Publicado: (2016)

Mast Cells as Cellular Sensors in Inflammation and Immunity
por: Beghdadi, Walid, et al.
Publicado: (2011)

Maturation of mast cell progenitors to mucosal mast cells during allergic pulmonary inflammation in mice
por: Bankova, LG, et al.
Publicado: (2014)

Mast cells infiltration and decreased E-cadherin expression in ketamine-induced cystitis
por: Li, Mengqiang, et al.
Publicado: (2014)

Neutralization of Interleukin-9 Decreasing Mast Cells Infiltration in Experimental Autoimmune Encephalomyelitis
por: Yin, Jun-Jie, et al.
Publicado: (2017)

Immune Cell Infiltration Analysis Demonstrates Excessive Mast Cell Activation in Psoriasis
por: Zhang, Yongjun, et al.
Publicado: (2021)

Tumor-infiltrating mast cells are associated with resistance to anti-PD-1 therapy
por: Somasundaram, Rajasekharan, et al.
Publicado: (2021)

Phospholipase A/acyltransferase 4 is a prognostic biomarker and correlated with immune infiltrates in pancreatic cancer
por: Li, Tian-Hao, et al.
Publicado: (2022)

Articular inflammation induced by an enzymatically-inactive Lys49 phospholipase A(2): activation of endogenous phospholipases contributes to the pronociceptive effect
por: Dias, Renata Gonçalves, et al.
Publicado: (2017)

Lessons from a Single Amino Acid Substitution: Anticancer and Antibacterial Properties of Two Phospholipase A(2)-Derived Peptides
por: Almeida, José R., et al.
Publicado: (2021)

Biochemical Characterization and Pharmacological Properties of New Basic PLA(2) BrTX-I Isolated from Bothrops roedingeri (Roedinger's Lancehead) Mertens, 1942, Snake Venom
por: Gomes Heleno, Mauricio Aurelio, et al.
Publicado: (2013)

The role of IL-33 and mast cells in allergy and inflammation
por: Saluja, Rohit, et al.
Publicado: (2015)

Elaeocarpusin Inhibits Mast Cell-Mediated Allergic Inflammation
por: Kim, Min-Jong, et al.
Publicado: (2018)

Editorial: Mast Cells in Itch, Pain and Neuro-Inflammation
por: Giniatullin, Rashid, et al.
Publicado: (2019)

Mast Cells in the Skin: Defenders of Integrity or Offenders in Inflammation?
por: Voss, Martin, et al.
Publicado: (2021)

Infiltrating Mast Cells Correlate with Angiogenesis in Bone Metastases from Gastric Cancer Patients
por: Ammendola, Michele, et al.
Publicado: (2015)

The relationship between histologic grades of invasive carcinoma of breast ducts and mast cell infiltration
por: Fakhrjou, Ashraf, et al.
Publicado: (2016)

Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential
por: Roy, Ananya, et al.
Publicado: (2017)

High infiltration of mast cells is associated with improved response to adjuvant chemotherapy in gallbladder cancer
por: Bo, Xiaobo, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_vgp04engg1647jpl022aq7f1lt