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Influence of chemical denaturants on the activity, fold and zinc status of anthrax lethal factor

Anthrax lethal factor (LF) is a zinc-dependent endopeptidase which, through a process facilitated by protective antigen, translocates to the host cell cytosol in a partially unfolded state. In the current report, the influence of urea and guanidine hydrochloride (GdnHCl) on LF׳s catalytic function,...

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Detalles Bibliográficos
Autores principales:	Lo, Suet Y., Säbel, Crystal E., Mapletoft, Jonathan P.J., Siemann, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668564/ https://www.ncbi.nlm.nih.gov/pubmed/29124135 http://dx.doi.org/10.1016/j.bbrep.2015.03.004

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