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HaCaT anchorage blockade leads to oxidative stress, DNA damage and DNA methylation changes

Cell adhesion plays an important role in neoplastic transformation. Thus, anchorage-independent growth and epithelial-mesenchymal transition, which are features associated to anoikis-resistance, are vital steps in cancer progression and metastatic colonization. Cell attachment loss may induce intrac...

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Detalles Bibliográficos
Autores principales: da Silva, Rodrigo A., Sammartino Mariano, Flavia, Planello, Aline. C., Line, Sergio R.P., de Souza, Ana Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668640/
https://www.ncbi.nlm.nih.gov/pubmed/29124149
http://dx.doi.org/10.1016/j.bbrep.2015.05.008