Interleukin-6/STAT pathway is responsible for the induction of gene expression of REG Iα, a new auto-antigen in Sjögren׳s syndrome patients, in salivary duct epithelial cells

The regenerating gene, Reg, was originally isolated from a rat regenerating islet cDNA library, and its human homolog was named REG Iα. Recently, we reported that REG Iα mRNA as well as its product were overexpressed in ductal epithelial cells in the minor salivary glands of Sjögren׳s syndrome (SS)...

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Detalles Bibliográficos
Autores principales: Fujimura, Takanori, Fujimoto, Takashi, Itaya-Hironaka, Asako, Miyaoka, Tomoko, Yoshimoto, Kiyomi, Yamauchi, Akiyo, Sakuramoto-Tsuchida, Sumiyo, Kondo, Saori, Takeda, Maiko, Tsujinaka, Hiroki, Azuma, Masayuki, Tanaka, Yasuhito, Takasawa, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668644/
https://www.ncbi.nlm.nih.gov/pubmed/29124146
http://dx.doi.org/10.1016/j.bbrep.2015.05.006

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