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Comparative gene expression profiles in pancreatic islets associated with agouti yellow mutation and PACAP overexpression in mice
In diabetes mellitus, pituitary adenylate cyclase-activating polypeptide (PACAP) has insulinotropic and glucose-lowering properties. We previously demonstrated that transgenic mice overexpressing PACAP in pancreatic β-cells (PACAP-Tg) show attenuated pancreatic islet hyperplasia and hyperinsulinemia...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668656/ https://www.ncbi.nlm.nih.gov/pubmed/29124161 http://dx.doi.org/10.1016/j.bbrep.2015.06.006 |