Cargando…

Comparative gene expression profiles in pancreatic islets associated with agouti yellow mutation and PACAP overexpression in mice

In diabetes mellitus, pituitary adenylate cyclase-activating polypeptide (PACAP) has insulinotropic and glucose-lowering properties. We previously demonstrated that transgenic mice overexpressing PACAP in pancreatic β-cells (PACAP-Tg) show attenuated pancreatic islet hyperplasia and hyperinsulinemia...

Descripción completa

Detalles Bibliográficos
Autores principales: Ikeda, Kazuya, Tomimoto, Shuhei, Tsuchiya, Soken, Hamagami, Ken-ichi, Shintani, Norihito, Sugimoto, Yukihiko, Ichikawa, Atsushi, Kasai, Atsushi, Nakazawa, Takanobu, Nagayasu, Kazuki, Hayata-Takano, Atsuko, Baba, Akemichi, Hashimoto, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668656/
https://www.ncbi.nlm.nih.gov/pubmed/29124161
http://dx.doi.org/10.1016/j.bbrep.2015.06.006