Impaired p65 degradation by decreased chaperone-mediated autophagy activity facilitates epithelial-to-mesenchymal transition

Aberrant activation of nuclear factor-κB (NF-κB) has been observed in a wide range of human cancers and is thought to promote tumorigenesis and metastasis. As a central component of NF-κB pathway, p65 protein level is tightly regulated and could be subjected to proteasome degradation. Here we demons...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, J, Zhan, M-N, Yin, Q-Q, Zhou, C-X, Wang, C-L, Wo, L-L, He, M, Chen, G-Q, Zhao, Q
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668883/
https://www.ncbi.nlm.nih.gov/pubmed/28991259
http://dx.doi.org/10.1038/oncsis.2017.85

Ejemplares similares

Ejemplares similares