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HiCRep: assessing the reproducibility of Hi-C data using a stratum-adjusted correlation coefficient
Hi-C is a powerful technology for studying genome-wide chromatin interactions. However, current methods for assessing Hi-C data reproducibility can produce misleading results because they ignore spatial features in Hi-C data, such as domain structure and distance dependence. We present HiCRep, a fra...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668950/ https://www.ncbi.nlm.nih.gov/pubmed/28855260 http://dx.doi.org/10.1101/gr.220640.117 |