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Biosensor-aided high-throughput screening of hyper-producing cells for malonyl-CoA-derived products

BACKGROUND: Malonyl-coenzyme A (CoA) is an important biosynthetic precursor in vivo. Although Escherichia coli is a useful organism for biosynthetic applications, its malonyl-CoA level is too low. RESULTS: To identify strains with the best potential for enhanced malonyl-CoA production, we developed...

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Detalles Bibliográficos
Autores principales: Li, Heng, Chen, Wei, Jin, Ruinan, Jin, Jian-Ming, Tang, Shuang-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669015/
https://www.ncbi.nlm.nih.gov/pubmed/29096626
http://dx.doi.org/10.1186/s12934-017-0794-6