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Reoxygenation Reverses Hypoxic Pulmonary Arterial Remodeling by Inducing Smooth Muscle Cell Apoptosis via Reactive Oxygen Species–Mediated Mitochondrial Dysfunction

BACKGROUND: Pulmonary arterial remodeling, a main characteristic of hypoxic pulmonary hypertension, can gradually reverse once oxygen has been restored. Previous studies documented that apoptosis increased markedly during the reversal of remodeled pulmonary arteries, but the types of cells and mecha...

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Detalles Bibliográficos
Autores principales:	Chen, Jian, Wang, Yan‐Xia, Dong, Ming‐Qing, Zhang, Bo, Luo, Ying, Niu, Wen, Li, Zhi‐Chao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669176/ https://www.ncbi.nlm.nih.gov/pubmed/28645933 http://dx.doi.org/10.1161/JAHA.117.005602

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