Cargando…
Curcuminoid–BF(2) complexes: Synthesis, fluorescence and optimization of BF(2) group cleavage
Eight difluoroboron complexes of curcumin derivatives carrying alkyne groups containing substituents have been synthesized following an optimised reaction pathway. The complexes were received in yields up to 98% and high purities. Their properties as fluorescent dyes have been investigated. Furtherm...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669223/ https://www.ncbi.nlm.nih.gov/pubmed/29114330 http://dx.doi.org/10.3762/bjoc.13.223 |
| _version_ | 1783275817626763264 |
|---|---|
| author | Weiss, Henning Reichel, Jeannine Görls, Helmar Schneider, Kilian Rolf Anton Micheel, Mathias Pröhl, Michael Gottschaldt, Michael Dietzek, Benjamin Weigand, Wolfgang |
| author_facet | Weiss, Henning Reichel, Jeannine Görls, Helmar Schneider, Kilian Rolf Anton Micheel, Mathias Pröhl, Michael Gottschaldt, Michael Dietzek, Benjamin Weigand, Wolfgang |
| author_sort | Weiss, Henning |
| collection | PubMed |
| description | Eight difluoroboron complexes of curcumin derivatives carrying alkyne groups containing substituents have been synthesized following an optimised reaction pathway. The complexes were received in yields up to 98% and high purities. Their properties as fluorescent dyes have been investigated. Furthermore, a strategy for the hydrolysis of the BF(2) group has been established using aqueous methanol and sodium hydroxide or triethylamine. |
| format | Online Article Text |
| id | pubmed-5669223 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2017 |
| publisher | Beilstein-Institut |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-56692232017-11-07 Curcuminoid–BF(2) complexes: Synthesis, fluorescence and optimization of BF(2) group cleavage Weiss, Henning Reichel, Jeannine Görls, Helmar Schneider, Kilian Rolf Anton Micheel, Mathias Pröhl, Michael Gottschaldt, Michael Dietzek, Benjamin Weigand, Wolfgang Beilstein J Org Chem Full Research Paper Eight difluoroboron complexes of curcumin derivatives carrying alkyne groups containing substituents have been synthesized following an optimised reaction pathway. The complexes were received in yields up to 98% and high purities. Their properties as fluorescent dyes have been investigated. Furthermore, a strategy for the hydrolysis of the BF(2) group has been established using aqueous methanol and sodium hydroxide or triethylamine. Beilstein-Institut 2017-10-26 /pmc/articles/PMC5669223/ /pubmed/29114330 http://dx.doi.org/10.3762/bjoc.13.223 Text en Copyright © 2017, Weiss et al. https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
| spellingShingle | Full Research Paper Weiss, Henning Reichel, Jeannine Görls, Helmar Schneider, Kilian Rolf Anton Micheel, Mathias Pröhl, Michael Gottschaldt, Michael Dietzek, Benjamin Weigand, Wolfgang Curcuminoid–BF(2) complexes: Synthesis, fluorescence and optimization of BF(2) group cleavage |
| title | Curcuminoid–BF(2) complexes: Synthesis, fluorescence and optimization of BF(2) group cleavage |
| title_full | Curcuminoid–BF(2) complexes: Synthesis, fluorescence and optimization of BF(2) group cleavage |
| title_fullStr | Curcuminoid–BF(2) complexes: Synthesis, fluorescence and optimization of BF(2) group cleavage |
| title_full_unstemmed | Curcuminoid–BF(2) complexes: Synthesis, fluorescence and optimization of BF(2) group cleavage |
| title_short | Curcuminoid–BF(2) complexes: Synthesis, fluorescence and optimization of BF(2) group cleavage |
| title_sort | curcuminoid–bf(2) complexes: synthesis, fluorescence and optimization of bf(2) group cleavage |
| topic | Full Research Paper |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669223/ https://www.ncbi.nlm.nih.gov/pubmed/29114330 http://dx.doi.org/10.3762/bjoc.13.223 |
| work_keys_str_mv | AT weisshenning curcuminoidbf2complexessynthesisfluorescenceandoptimizationofbf2groupcleavage AT reicheljeannine curcuminoidbf2complexessynthesisfluorescenceandoptimizationofbf2groupcleavage AT gorlshelmar curcuminoidbf2complexessynthesisfluorescenceandoptimizationofbf2groupcleavage AT schneiderkilianrolfanton curcuminoidbf2complexessynthesisfluorescenceandoptimizationofbf2groupcleavage AT micheelmathias curcuminoidbf2complexessynthesisfluorescenceandoptimizationofbf2groupcleavage AT prohlmichael curcuminoidbf2complexessynthesisfluorescenceandoptimizationofbf2groupcleavage AT gottschaldtmichael curcuminoidbf2complexessynthesisfluorescenceandoptimizationofbf2groupcleavage AT dietzekbenjamin curcuminoidbf2complexessynthesisfluorescenceandoptimizationofbf2groupcleavage AT weigandwolfgang curcuminoidbf2complexessynthesisfluorescenceandoptimizationofbf2groupcleavage |