Cargando…
An efficient synthesis of a C(12)-higher sugar aminoalditol
The C(12)-aminoalditol H(2)NCH(2)–(CHOBn)(10)–CH(2)OH was prepared from two simple monosaccharide building blocks. The synthesis was realized by a regioselective introduction of the azide group and subsequent protection–deprotection transformations. The chemical reactivity of the aminoalditol was te...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669227/ https://www.ncbi.nlm.nih.gov/pubmed/29114320 http://dx.doi.org/10.3762/bjoc.13.213 |
_version_ | 1783275818562093056 |
---|---|
author | Szyszka, Łukasz Osuch-Kwiatkowska, Anna Potopnyk, Mykhaylo A Jarosz, Sławomir |
author_facet | Szyszka, Łukasz Osuch-Kwiatkowska, Anna Potopnyk, Mykhaylo A Jarosz, Sławomir |
author_sort | Szyszka, Łukasz |
collection | PubMed |
description | The C(12)-aminoalditol H(2)NCH(2)–(CHOBn)(10)–CH(2)OH was prepared from two simple monosaccharide building blocks. The synthesis was realized by a regioselective introduction of the azide group and subsequent protection–deprotection transformations. The chemical reactivity of the aminoalditol was tested in the reductive amination reaction with a selectively protected sucrose monoaldehyde. |
format | Online Article Text |
id | pubmed-5669227 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Beilstein-Institut |
record_format | MEDLINE/PubMed |
spelling | pubmed-56692272017-11-07 An efficient synthesis of a C(12)-higher sugar aminoalditol Szyszka, Łukasz Osuch-Kwiatkowska, Anna Potopnyk, Mykhaylo A Jarosz, Sławomir Beilstein J Org Chem Full Research Paper The C(12)-aminoalditol H(2)NCH(2)–(CHOBn)(10)–CH(2)OH was prepared from two simple monosaccharide building blocks. The synthesis was realized by a regioselective introduction of the azide group and subsequent protection–deprotection transformations. The chemical reactivity of the aminoalditol was tested in the reductive amination reaction with a selectively protected sucrose monoaldehyde. Beilstein-Institut 2017-10-16 /pmc/articles/PMC5669227/ /pubmed/29114320 http://dx.doi.org/10.3762/bjoc.13.213 Text en Copyright © 2017, Szyszka et al. https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
spellingShingle | Full Research Paper Szyszka, Łukasz Osuch-Kwiatkowska, Anna Potopnyk, Mykhaylo A Jarosz, Sławomir An efficient synthesis of a C(12)-higher sugar aminoalditol |
title | An efficient synthesis of a C(12)-higher sugar aminoalditol |
title_full | An efficient synthesis of a C(12)-higher sugar aminoalditol |
title_fullStr | An efficient synthesis of a C(12)-higher sugar aminoalditol |
title_full_unstemmed | An efficient synthesis of a C(12)-higher sugar aminoalditol |
title_short | An efficient synthesis of a C(12)-higher sugar aminoalditol |
title_sort | efficient synthesis of a c(12)-higher sugar aminoalditol |
topic | Full Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669227/ https://www.ncbi.nlm.nih.gov/pubmed/29114320 http://dx.doi.org/10.3762/bjoc.13.213 |
work_keys_str_mv | AT szyszkałukasz anefficientsynthesisofac12highersugaraminoalditol AT osuchkwiatkowskaanna anefficientsynthesisofac12highersugaraminoalditol AT potopnykmykhayloa anefficientsynthesisofac12highersugaraminoalditol AT jaroszsławomir anefficientsynthesisofac12highersugaraminoalditol AT szyszkałukasz efficientsynthesisofac12highersugaraminoalditol AT osuchkwiatkowskaanna efficientsynthesisofac12highersugaraminoalditol AT potopnykmykhayloa efficientsynthesisofac12highersugaraminoalditol AT jaroszsławomir efficientsynthesisofac12highersugaraminoalditol |