Cargando…

Conjugated nitrosoalkenes as Michael acceptors in carbon–carbon bond forming reactions: a review and perspective

Despite of their chemical instability and high reactivity, conjugated nitrosoalkenes are useful intermediates in target-oriented organic synthesis. The present review deals with carbon–carbon bond forming reactions involving Michael addition to α-nitrosoalkenes with a particular focus on recent deve...

Descripción completa

Detalles Bibliográficos
Autores principales: Boyko, Yaroslav Dmitrievich, Dorokhov, Valentin Sergeevich, Sukhorukov, Alexey Yu, Ioffe, Sema Leibovich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669230/
https://www.ncbi.nlm.nih.gov/pubmed/29114327
http://dx.doi.org/10.3762/bjoc.13.220
Descripción
Sumario:Despite of their chemical instability and high reactivity, conjugated nitrosoalkenes are useful intermediates in target-oriented organic synthesis. The present review deals with carbon–carbon bond forming reactions involving Michael addition to α-nitrosoalkenes with a particular focus on recent developments in this methodology and its use in total synthesis.