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Atomic model of a non-enveloped virus reveals pH sensors for a coordinated process of cell entry

Viruses sense environmental cues (such as pH) to engage in membrane interactions for cell entry during infection but how non-enveloped viruses sense pH is largely undefined. Here, we report the structures — at high and low pH conditions — of bluetongue virus (BTV), which enters cells via a two-stage...

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Detalles Bibliográficos
Autores principales: Zhang, Xing, Patel, Avnish, Celma, Cristina C., Yu, Xuekui, Roy, Polly, Zhou, Z. Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669276/
https://www.ncbi.nlm.nih.gov/pubmed/26641711
http://dx.doi.org/10.1038/nsmb.3134