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Production, in Pichia pastoris, of a recombinant monomeric mapacalcine, a protein with anti-ischemic properties()
Mapacalcine is a small homodimeric protein of 19 kDa with 9 disulfide bridges extracted from the Cliona vastifica sponge (Red Sea). It selectively blocks a calcium current insensitive to most calcium blockers. Specific receptors for mapacalcine have been described in a variety of tissues such as bra...
Autores principales: | Noubhani, A., Bégu, D., Chaignepain, S., Moha ou Maati, H., Borsotto, M., Dupuy, J.W., Langlois d'Estaintot, B., Santarelli, X., Heurteaux, C., Gallois, B., Hugues, M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669352/ https://www.ncbi.nlm.nih.gov/pubmed/29124217 http://dx.doi.org/10.1016/j.bbrep.2015.10.003 |
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