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Investigation of FoxO3 dynamics during erythroblast development in β-thalassemia major

The FoxO3 transcription factor is a key regulator of oxidative stress and erythroid maturation during erythropoiesis. In this study, we explored the involvement of FoxO3 in severe β-thalassemia. Using primary CD34(+) hematopoietic progenitor cells from patients with β-thalassemia major, we successfu...

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Detalles Bibliográficos
Autores principales:	Thanuthanakhun, Naruchit, Nuntakarn, Lalana, Sampattavanich, Somponnat, Anurathapan, Usanarat, Phuphanitcharoenkun, Suphanun, Pornpaiboonstid, Savichaya, Borwornpinyo, Suparerk, Hongeng, Suradej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669432/ https://www.ncbi.nlm.nih.gov/pubmed/29099866 http://dx.doi.org/10.1371/journal.pone.0187610

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