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Fibrinogen and clot-related phenotypes determined by fibrinogen polymorphisms: Independent and IL-6-interactive associations
Interleukin-6 (IL-6) induces the expression of fibrinogen, and polymorphic variation within the fibrinogen genes is believed to alter the magnitude of this expression. The identification of the functional relevance of individual fibrinogen single nucleotide polymorphisms (SNPs) has been hindered by...
Autores principales: | Cronjé, H. Toinét, Nienaber-Rousseau, Cornelie, Zandberg, Lizelle, de Lange, Zelda, Green, Fiona R., Pieters, Marlien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669433/ https://www.ncbi.nlm.nih.gov/pubmed/29099861 http://dx.doi.org/10.1371/journal.pone.0187712 |
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