Knockout of Apolipoprotein E in rabbit promotes premature intervertebral disc degeneration: A new in vivo model for therapeutic approaches of spinal disc disorders

Intervertebral disc (IVD) degeneration that accelerates the loss of disc structural and functional integrities is recognized as one of the major factors of chronic back pain. Cardiovascular risk factors, such as deficits of apolipoproteins that elevate the levels of cholesterol and triglycerides, ar...

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Detalles Bibliográficos
Autores principales: Beierfuß, Anja, Dietrich, Hermann, Kremser, Christian, Hunjadi, Monika, Ritsch, Andreas, Rülicke, Thomas, Thomé, Claudius, Mern, Demissew Shenegelegn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669473/
https://www.ncbi.nlm.nih.gov/pubmed/29099857
http://dx.doi.org/10.1371/journal.pone.0187564

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