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Prediction of HIV-1 sensitivity to broadly neutralizing antibodies shows a trend towards resistance over time
Treatment with broadly neutralizing antibodies (bNAbs) has proven effective against HIV-1 infections in humanized mice, non-human primates, and humans. Due to the high mutation rate of HIV-1, resistance testing of the patient’s viral strains to the bNAbs is still inevitable. So far, bNAb resistance...
Autores principales: | Hake, Anna, Pfeifer, Nico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669501/ https://www.ncbi.nlm.nih.gov/pubmed/29065122 http://dx.doi.org/10.1371/journal.pcbi.1005789 |
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