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Gastrointestinal Side Effects of Antiarrhythmic Medications: A Review of Current Literature

Antiarrhythmic drugs are commonly prescribed cardiac drugs. Due to their receptor mimicry with several of the gastrointestinal tract receptors, they can frequently lead to gastrointestinal side effects. These side effects are the most common reasons for discontinuation of these drugs by the patients...

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Detalles Bibliográficos
Autores principales: Amjad, Waseem, Qureshi, Waqas, Farooq, Ali, Sohail, Umair, Khatoon, Salma, Pervaiz, Sarah, Narra, Pratyusha, Hasan, Syeda M, Ali, Farman, Ullah, Aman, Guttmann, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669531/
https://www.ncbi.nlm.nih.gov/pubmed/29142794
http://dx.doi.org/10.7759/cureus.1646
Descripción
Sumario:Antiarrhythmic drugs are commonly prescribed cardiac drugs. Due to their receptor mimicry with several of the gastrointestinal tract receptors, they can frequently lead to gastrointestinal side effects. These side effects are the most common reasons for discontinuation of these drugs by the patients. Knowledge of these side effects is important for clinicians that manage antiarrhythmic drugs. This review focuses on the gastrointestinal side effects of these drugs and provides a detailed up-to-date literature review of the side effects of these drugs. The review provides case reports reported in the literature as well as possible mechanisms that lead to gastrointestinal side effects.