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5-Aza-2′-deoxycytidine protects against emphysema in mice via suppressing p16(Ink4a) expression in lung tissue

BACKGROUND: There is a growing realization that COPD, or at least emphysema, involves several processes presenting in aging and cellular senescence. Endothelial progenitor cells (EPCs) contribute to neovascularization and play an important role in the development of COPD. The gene for p16(Ink4a) is...

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Detalles Bibliográficos
Autores principales:	He, Zhi-Hui, Chen, Yan, Chen, Ping, He, Sheng-Dong, Zeng, Hui-Hui, Ye, Ji-Ru, Liu, Da, Cao, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669795/ https://www.ncbi.nlm.nih.gov/pubmed/29133977 http://dx.doi.org/10.2147/COPD.S131090

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