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Aberrantly activated Cox-2 and Wnt signaling interact to maintain cancer stem cells in glioblastoma

Glioblastoma recurrence after aggressive therapy typically occurs within six months, and patients inevitably succumb to their disease. Tumor recurrence is driven by a subpopulation of cancer stem cells in glioblastoma (glioblastoma stem-like cells, GSCs), which exhibit resistance to cytotoxic therap...

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Detalles Bibliográficos
Autores principales: Wu, Megan, Guan, Jennifer, Li, Chris, Gunter, Simon, Nusrat, Labeeba, Ng, Sheena, Dhand, Karan, Morshead, Cindi, Kim, Albert, Das, Sunit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669884/
https://www.ncbi.nlm.nih.gov/pubmed/29137258
http://dx.doi.org/10.18632/oncotarget.19283

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