Genetic and immune features of resectable malignant brainstem gliomas

We surveyed common genetic mutations (IDH1, H3F3A, PPM1D, and TP53) and immune features (PD-L1 expression and CD8(+) T cell tumor infiltration) in a series of 62 malignant brainstem gliomas that were resected via microsurgery. IDH1 mutations were mutually exclusive with H3F3A mutations. IDH1 mutatio...

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Detalles Bibliográficos
Autores principales: Zhang, Yang, Pan, Changcun, Wang, Junmei, Cao, Jingli, Liu, Yuhan, Wang, Yajie, Zhang, Liwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669911/
https://www.ncbi.nlm.nih.gov/pubmed/29137285
http://dx.doi.org/10.18632/oncotarget.19653

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