Elevated TIMP-1 expression is associated with a prometastatic phenotype, disease relapse, and poor survival in neuroblastoma

Approximately two-thirds of patients with neuroblastoma are found to have metastatic disease at time of diagnosis with frequent skeletal, lymph node, central nervous system, and liver involvement. Using a serial in vivo splenic injection model, we have isolated an aggressive subclone (BE(2)-C/LM2) f...

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Detalles Bibliográficos
Autores principales: Paul, Pritha, Rellinger, Eric J., Qiao, Jingbo, Lee, Sora, Volny, Natasha, Padmanabhan, Chandrasekhar, Romain, Carmelle V., Mobley, Bret, Correa, Hernan, Chung, Dai H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669914/
https://www.ncbi.nlm.nih.gov/pubmed/29137288
http://dx.doi.org/10.18632/oncotarget.19664

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