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Reversal of 5-fluorouracil resistance by EGCG is mediate by inactivation of TFAP2A/VEGF signaling pathway and down-regulation of MDR-1 and P-gp expression in gastric cancer
The effect of 5-fluorouracil (5-FU) chemotherapy for gastric cancer (GC) is limited by drug-resistance. To conquer this drug-resistance, various treatments including combination therapy have been used, but the overall survival has not been improved yet. In our current study, 5-FU resistant GC cells,...
Autores principales: | Tang, Hongsheng, Zeng, Lisi, Wang, Jiahong, Zhang, Xiangliang, Ruan, Qiang, Wang, Jin, Cui, Shuzhong, Yang, Dinghua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669933/ https://www.ncbi.nlm.nih.gov/pubmed/29137307 http://dx.doi.org/10.18632/oncotarget.20666 |
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