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Deletion of Cdc42 in embryonic cardiomyocytes results in right ventricle hypoplasia

BACKGROUND: Cdc42 is a member of the Rho GTPase family and functions as a molecular switch in regulating cytoskeleton remodeling and cell polarity establishment. Inactivating Cdc42 in cardiomyocytes resulted in embryonic lethality with heart developmental defects, including ventricular septum defect...

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Detalles Bibliográficos
Autores principales:	Liu, Yang, Wang, Jian, Li, Jieli, Wang, Rui, Tharakan, Binu, Zhang, Shenyuan L., Tong, Carl W., Peng, Xu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2017
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670094/ https://www.ncbi.nlm.nih.gov/pubmed/29101495 http://dx.doi.org/10.1186/s40169-017-0171-4

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