Cargando…
Folding of a bacterial integral outer membrane protein is initiated in the periplasm
The Bam complex promotes the insertion of β-barrel proteins into the bacterial outer membrane, but it is unclear whether it threads β-strands into the lipid bilayer in a stepwise fashion or catalyzes the insertion of pre-folded substrates. Here, to distinguish between these two possibilities, we ana...
Autores principales: | Sikdar, Rakesh, Peterson, Janine H., Anderson, D. Eric, Bernstein, Harris D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670179/ https://www.ncbi.nlm.nih.gov/pubmed/29101319 http://dx.doi.org/10.1038/s41467-017-01246-4 |
Ejemplares similares
-
Sequential Translocation of Polypeptides across the Bacterial Outer Membrane through the Trimeric Autotransporter Pathway
por: Sikdar, Rakesh, et al.
Publicado: (2019) -
Bacterial Outer Membrane Proteins Are Targeted to the Bam Complex by Two Parallel Mechanisms
por: Wang, Xu, et al.
Publicado: (2021) -
Effects of Periplasmic Chaperones and Membrane Thickness on BamA-Catalyzed Outer-Membrane Protein Folding
por: Schiffrin, Bob, et al.
Publicado: (2017) -
Dissecting the Effects of Periplasmic Chaperones on the In Vitro Folding of the Outer Membrane Protein PagP
por: McMorran, Lindsay M., et al.
Publicado: (2013) -
Small Molecule Antibiotics Inhibit Distinct Stages of Bacterial Outer Membrane Protein Assembly
por: Peterson, Janine H., et al.
Publicado: (2022)