Reactivity and sensitivity of commercially available influenza rapid diagnostic tests in Japan

Seasonal influenza virus routinely causes epidemic infections throughout the world. Sporadic infections by H5N1, H5N6, and H7N9 viruses are also reported. To treat patients suffering from such viral infections, broadly reactive and highly sensitive influenza rapid diagnostic tests (IRDTs) are requir...

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Detalles Bibliográficos
Autores principales: Sakai-Tagawa, Yuko, Yamayoshi, Seiya, Kawakami, Chiharu, Le, Mai Q., Uchida, Yuko, Saito, Takehiko, Nidom, Chairul A., Humaira, Ira, Toohey-Kurth, Kathy, Arafa, Abdel-Satar, Liu, Ming-Tsan, Shu, Yuelong, Kawaoka, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670212/
https://www.ncbi.nlm.nih.gov/pubmed/29101372
http://dx.doi.org/10.1038/s41598-017-14536-0
Descripción
Sumario:Seasonal influenza virus routinely causes epidemic infections throughout the world. Sporadic infections by H5N1, H5N6, and H7N9 viruses are also reported. To treat patients suffering from such viral infections, broadly reactive and highly sensitive influenza rapid diagnostic tests (IRDTs) are required. Here, we examined the reactivity and sensitivity of 25 IRDTs available in Japan for the detection of seasonal H1N1pdm09, H3N2, and type B viruses, as well as highly pathogenic H5 and H7 viruses. All of the IRDTs tested detected the seasonal viruses and H5 and H7 viruses albeit with different sensitivities. Several IRDTs detected the H5 and H7 viruses and the seasonal viruses with similar (high) sensitivity.

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