Trichostatin A ameliorates renal tubulointerstitial fibrosis through modulation of the JNK-dependent Notch-2 signaling pathway

Renal fibrosis is the final common pathological feature in a variety of chronic kidney disease. Trichostatin A (TSA), a histone deacetylase inhibitor, reportedly attenuates renal fibrosis in various kidney disease models. However, the detailed molecular action of TSA in ameliorating renal fibrotic i...

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Detalles Bibliográficos
Autores principales: Tung, Chun-Wu, Hsu, Yung-Chien, Cai, Chang-Jhih, Shih, Ya-Hsueh, Wang, Ching-Jen, Chang, Pey-Jium, Lin, Chun-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670251/
https://www.ncbi.nlm.nih.gov/pubmed/29101337
http://dx.doi.org/10.1038/s41598-017-15162-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670251/
https://www.ncbi.nlm.nih.gov/pubmed/29101337
http://dx.doi.org/10.1038/s41598-017-15162-6

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