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Butyrate Conditions Human Dendritic Cells to Prime Type 1 Regulatory T Cells via both Histone Deacetylase Inhibition and G Protein-Coupled Receptor 109A Signaling

Recently, it has become clear that short-chain fatty acids (SCFAs), and in particular butyrate, have anti-inflammatory properties. Murine studies have shown that butyrate can promote regulatory T cells via the induction of tolerogenic dendritic cells (DCs). However, the effects of SCFAs on human DCs...

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Detalles Bibliográficos
Autores principales:	Kaisar, Maria M. M., Pelgrom, Leonard R., van der Ham, Alwin J., Yazdanbakhsh, Maria, Everts, Bart
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670331/ https://www.ncbi.nlm.nih.gov/pubmed/29163504 http://dx.doi.org/10.3389/fimmu.2017.01429

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