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The effect of long-term bisphosphonate therapy on trabecular bone strength and microcrack density

OBJECTIVES: Bisphosphonates (BP) are the first-line treatment for preventing fragility fractures. However, concern regarding their efficacy is growing because bisphosphonate is associated with over-suppression of remodelling and accumulation of microcracks. While dual-energy X-ray absorptiometry (DX...

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Detalles Bibliográficos
Autores principales: Jin, A., Cobb, J., Hansen, U., Bhattacharya, R., Reinhard, C., Vo, N., Atwood, R., Li, J., Karunaratne, A., Wiles, C., Abel, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670367/
https://www.ncbi.nlm.nih.gov/pubmed/29066534
http://dx.doi.org/10.1302/2046-3758.610.BJR-2016-0321.R1